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Charles Wambebe

Charles Obadiah Nimma Wambebe, Nigerian pharmacologist (Emi-Tsado, Benu State 08 August 1946 -

Authored over 150 papers


CONTRIBUTIONS

Developed drugs from local plants for the treatment of sickle cell anaemia, peptic ulcer, tropical skin infection and diabetes

Developed a technique of HPLC for simultaneous determination of monoamines

With D. Naur & G. Osuide. Simultaneous determination of monoamines and their principal metabolites in brain tissue of the young chick by reversed-phase ion-pair high performance liquid chromatography. J. Pharmacol. Biomed. Anal. 7(7):899-905, 1989


PAPERS IN TOP JOURNALS

With K. Bryc, A. Auton, M.R. Nelson, J.R. Oksenberg, S.L. Hauser et al. Genome-wide patterns of population structure and admixture in West Africans and African Americans. Proceed. Natl. Acad. Sci. 107(2):786-91, 2010

With S.A. Tishkoff, F.A. Reed, F.R. Friedlaender, C. Ehret, A. Ranciaro et al. The genetic structure and history of Africans and African Americans. Science 324 (5930):1035-44, 2009


PATENTS

With P.O. Ogunyale, K.S. Gamaniel, R.N. Nasipuri, J.I. Okogun, B. Samuel, A. Olusola & A. Orisadipo. Piper guineense, Pterocarpus osun, Eugenia caryophylla and Sorghum bicolor extracts for treating sickle cell disease USPTO 5,800,819 (1998)

Phytodrug for treating skin fungal infections and methods of preparing and using the same. (NIPRIFAN) US5,840,310 (1998) and 40 countries

Phytodrug for management of peptic ulcer and method of preparing and using the same. (NIPRIPAN) Nigerian patent RP12581 & USPTO and 40 countries

Phytodrug for treating and management of sickle cell anemia and methods of preparing and using the same (NIPRISAN)


HONOURS

Twentieth Century Award for Achievement, International Biographical Centre, Cambridge (1998)