Oswaldo Vital Brazil, Brazilian pharmacologist and
toxinologist (São Paulo 02 March 1912 –Campinas, São Paulo State 26 October 2008) Son of physician Vital Brazil Gained international recognition on
action mechanisms of venoms and toxins from snakes, spiders and scorpions First application in man of anti Ctenus serum Imunização por via intradérmica e por via sub-cutânea pelo soro antictenus. Método de dosagem e primeira aplicação no homem. Anais Paul. Med. Cir. 60(5):555-63, 1950 Obtained, purified and clarified the
chemical structure of beeberine (1946-7) Isolated chondrocurare from Chondrodendrum platyphyllum (1942) used
as muscle relaxant Demonstrated pharmacological basis
of venom actions from snakes Micrurus
sp. and Crotalus sp. Discovered that 3,4 diaminopyridine
is able to inhibit dessensitization phenomenon (1983) With A. P. Corrado discovered neuromuscular action of
antibiotics and the blocking mechanism of streptomycin in high doses (1957) With J. Prado-Franceschi, M.G. Lomba
and N.F. Heluany discovered convulxine a new toxin from rattle snake venom
(1967) With A. Barrio described an
apparatus for obtaining bird spider venom employing electrical shock With M. Lomba, J.C. Barberio & J. Kieffer. A biosynthetic method for labeling snake venoms. Intern. Conference Radioactive Isotope in Pharmacol. (1969) |
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