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Alfredo Ulloa Aguirre

Alfredo Antonio Ulloa-Aguirre, Mexican reproductive endocrinologist (Ciudad de Mexico 1949 -

Authored over 180 papers, 42 book chapters with 7,800 citations (h-index 52)

Recognized internationally as expert on G-protein coupled proteins and a leader in the field of gonadotrophin heterogeneity

Developed laboratory methods to characterize the biochemical and biological features of follicle-stimulating glycoforms

Described hypogonadotrophic hypogonadism by hypothalamic dysfunction in Steinert disease (1975)

With G. Perez Palacios e M. Medina proposed new concepts on action mechanisms of sex steroidal hormones

With J.P. Mendez, A. Cravioto, E. Grotjan, P. Damián-Matsumura & R. Espinoza described and characterized biologically the human chorionic gonadotropin isotypes produced and secreted during the morphological and functional differentiation of the human cytotrophoblast in culture in Human Reprod. 5:661, 1990

With A. Cravioto, P. Damián Matsumura, M. Jimenez & E. Zambrano first detailled characterization of the biological attributes of the naturally occurring analogs of human follicle-stimulating hormone in Human Reprod. 7:23, 1992

With L. Díaz Cueto, J.P. Mendez & J.D. Veldhuis documented in humans the co-existence of a variety of biochemical and functional mechanisms by which the placenta and the pituitary gland regulate the biochemical composition and the intensity of gonadotropic stimulus in J. Clin. Endocrinol. Metab. 78:890, 1994 & 80:1647, 1995

With J.P. Mendez, S. Kofman-Alfaro, O. Mutchinick et al. established a detailed description of the clinical, cytogenetic, endocrinologic and histopathologic features of patients with gonada dysgenesis in Am. J. Med. Genet. 46:263, 1993

With J.P. Mendez, V. Díaz Sanchez, A. Altamirano & G. Perez Palacios described the development of a biphasic testicular response to exogenous hcG in J. Clin. Endocrinol. Metab. 61:926, 1985

With J. Larriva Sahd, L. Carrillo, H. Orozco & F. Larrea demonstrated that the human placenta is a site of sex hormone binding globlin gene expression. J. Steroid Biochem. Mol. Biol. 46:497, 1993