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Saenz Renauld brothers

Germán Federico Saenz Renauld, Costa Rican hematologist (23 December 1935 -



Presented a topographical classification of abnormal hemoglobins

Clasificación topografica de las hemoglobinas anormales. Rev. Biol. Trop. 24(1):57-68, 1976



HEMATOLOGY / GENETICS

With W.E. Rodríguez Romero, M. Castillo, M.A. Chaves, L.H. Gui, J.B. Wilson, E. Baysal, N. Smetanina, J.Y. Leonova & T.H.J. Huisman. Hb Costa Rica or α2β277(EF1) His→Arg: the first example of a somatic cell mutation in a globin gene. Human Genetics 97(6):829-33, 1996

With M.H. Wiehe Chaves, A. Berrantes, J. Elizondo, A.G. Montero & A. Yoshida. A glucose 6 phosphate dehydrogenase variant GD(-) Santamaria found in Costa Rica. Acta Hematologica 72(1):37-40, 1984

With J. Elizondo, C. Paez, M. Ramón, M. Garcia, A. Gutierrez & M. Micheld Estrada. G6PD Puerto Limón: a new deficient variant of glucose 6-phosphate dehydrogenase associated with congenital nonspherocytic hemolytic anemia. Human Genetics 62(2):110-2, 1982

With J. Elizondo, M. Alvarado, F. Ametlla, G. Arroyo, G. Martínez, F. Lima & B. Colombo. Chemical characterization of a new haemoglobin variant, haemoglobin Cubujuqui (α2141)(HC3)Arg replaced by Ser beta2). Biochim. Biophys. Acta 494(1):48-50, 1977


DEVELOPED METHODS

With N. Lobo, I. Holst, K. Schosinsky & M. Chaves. Creatinina intraeritrocitária como valoración de la edad celular. Rev. Costarric. Cien. Med. 11(3-4):27-33, 1990

With E.M. Quintana & M. Chaves. Soluciones patron y control para la medición de la hemoglobina como oxihemoglobina. Rev. Costarric. Cien. Med. 8(3):149-58, 1987

With M. Chaves, G. Arroyo, E. Valenciano & J. Jimenez. Hierro serico y transferrina funcional: capacidad total de fijación de hierro: preconización de una metodologia. Rev. Costarric. Cien. Med. 6(1):51-64, 1985

With E. Valenciano & K. Schosinsky. Experimental and critical approach to the assay of hemoglobin. Sangre 24(6):1133-41 1979

With M. Alvarado, J. Elizondo, G. Arroyo, F. Ametlla, J. Jimenez, G.M. Montero, R. Chavez, E. Valenciano & R.F. Jimenez. Haemogloblinopathies and related disoders. II. Presentation of the proposed screening methods. Sangre 23(4):489-502, 1978




José Alberto Saenz Renauld, Costa Rican plant chemist and mycologist (1929 -



DESCRIBED FUNGI TAXA

Genus

Ligiella 1980 (in honor to his wife Ligia)

Species

Ligiella rodrigueziana 1980

Pseudocolus grandis 1982 with Rawla & Sharma



NEW CHEMICALS

With G.R. Pettit, D.E. Schaufelberger, R.A. Niemann & C. Dufresne. Antineoplastic agents,177. Isolation and structure of phyllanthostatin 6. J. Nat. Prod. 53(6):1406-13, 1990

With G.R. Pettit, G.M. Cragg, M.I. Suffness, D. Gust, F.E. Boettner, M. Williams, P. Brown, J.M. Schmidt & P.D. Ellis. Antineoplastic agents 104. Isolation and structure of the Phyllanthus acuminatus Vahl (Euphorbiaceae) glycosides. J. Org. Chem. 49(22):4258-66, 1984

With S.M. Kupchan, C.W. Sigel, M.J. Matz, R.C. Haltiwanger & R.F. Bryan. Jatrophone, a novel macrocyclic diterpenoid tumor inhibitor from Jatropha gossypifolia. J. Am. Chem. Soc. 92(14):4476-7, 1970

With S.M. Kupchan, W.K. Anderson, P. Bollinger, R.W. Doskotch, R.M. Smith, H.K. Schnoes, S.L. Burlingame & D.H. Smith. Tumor inhibitors. XXXIX. Active principles of Acnistus arborescens. Isolation and structural and spectral studies of withaferin A and withacnistin. J. org. Chem. 34:3858, 1969

With M. Nassar-Carballo. Phytochemical screening of Costa Rican plants: alkaloid analysis. III. Rev. Biol. trop. 15:195-202, 1968

With S.M. Kupchan, R.W. Doskotch, P. Bollinger, A.T. McPhail & G.A. Sim. The isolation and structural isolation of a novel steroidal tumor inhibitor from Acnistus arborescens. J. Am. Chem. Soc. 87(24):805-6, 1965

With S.M. Kupchan, J.R. Kupchan, J.E. Knox & A. Kelsey. Calotropin, a cytotoxic principle isolated from Asclepias curassavica L. Science (1964)

With A. Ashok, T.G. McCloud, C.G. Chang & J.M. Cassidy. A novel cytotoxic deoxocucurbitacin from Desfontainea spinosa