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Arturo Rosenblueth Stearns

Arturo Rosenblueth Stearns, Mexican neurophysiologist (Ciudad Guerrero, Chihuahua State 02 October 1900 – Ciudad de Mexico 20 September 1970)

From Jewish Hungarian father and Irish-descent mother
Considered one of the world’s most important neurophysiologists and a founder of cybernetics
Authored 153 papers and 4 monographs

Demonstrated that DNA was the main responsible for genetic transmission (1944)


With Norbert Wiener

Set the bases of cybernetics

With N. Wiener & J. Bigelow. Behavior, Purpose and Teleology. Philosophy of Science 10(1):21, 1943 
Elaborated a mathematical model that describes impulses in a neuron network and perform a statistical analysis of communication process between neurons 
Discovered negative feedback in human organism 
Formulated mathematically cardiac impulse conduction (1946) 
First proposed the concept of vulnerability to formation of an unidirectional block and introduced a specific protocol of stimulation of an one-dimensional excitable ring 

With W.B. Cannon

Predicted the existence of noradrenaline (1933)
Elucidated the details of the sympathetic regulatory action
Proved chemical mediation of autonomic nervous impulses through synapses
Established quantitative laws that rule the action mode of nerve impulses

Determinated specific action of adrenaline released in striated muscles


Described in detail electrical phenomena that occur in smooth muscles
Described relative electrical instability of autonomous effectors, smooth muscles and glands
Enunciated Cannon-Rosenblueth law of denervation (1949)
Developed Rosenblueth-Cannon test for adrenaline
Authored a classical book Physiology of the Autonomous Nervous System (1937)

With others

With J. Luco Valenzuela demonstrated that during prolonged stimulation of a motor nerve, neuromuscular fatigue is followed by a rise of tension known as Rosenblueth phenomenon (1939) 
With J. Luco Valenzuela discovered fifth stage in neuromuscular transmission  
Distinguished between transmission fatigue and contraction fatigue
Developed Rosenblueth-García Ramos method (1947)
With Alanís and Mandoki enunciated concept of refractory functional period in nerve cell (1949)
Introduced nerve electrophysiology into the study of cardiac tissue

Enunciated mathematical laws that regulate striation and fibrillation of cardiac auricle 

With Daughaday-Bond & García Ramos described and systematized cardiac ventricle electrogram

Medicine & Physiology Nobel Prize nominee (1952)