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Alaide Braga de Oliveira

Alaíde Braga de Oliveira, Brazilian plant chemist (Morada Nova de Minas, Minas Gerais State 10 March 1941 –



NEW CHEMICALS

With L.R. Simões, G.M. Maciel, G.C. Brandão, J.D. Souza Filho & R.O. Castilho. Chemical constituents of Distictella elongata (Vahl) Urb. (Bignoniaceae). Anais Acad. Bras. Ciencias 85(3):873-9, 2013 (first report of a flavone heteroside in a species of the Bignoniaceae family)

With R. Batista, P.A. Garcia, M. Castro, JM. Miguel del Corral et al. Synthesis, cytotoxicity and antiplasmodial activity of novel ent-kaurane derivatives. Eur. J. Medic. Chem. 62C:168-76, 2012

With R. Batista, J.M. Miguel del Corral & A. San Feliciano. New oxidized ent-kaurane and ent-nor-kaurane derivatives from kaurenoic acid. J. Braz. Chem. Soc. 18:622-7, 2007

With J.M.Miguel del Corral, M. Castro, S. Gualberto, C. Cuevas & A. Feliciano. New cytotoxic furoquinones obtained from terpenyl-1,4 naphthoquinones and 1,4 anthracenediones. Bioorg. Medic. Chem. 14:7231-40, 2006

With T.H.A. Silva, M.T. Oliveira, H.F. Santos & W.B. Almeida. Estudo de modelagem molecular de complexos de ferriprotoporfirina IX e quinolinocarbinolaminas antimaláricas: proposta de um farmacóforo. Quimica Nova 28(2):244-9, 2005

With B.B. Cota, K.G. Guimarães, M.P. Mendonça, J.D. Souza Filho & F.C. Braga. Chemistry and antifungal activity of Xyris species (Xyridaceae): a new anthraquinone from Xyris pilosa. Biochem. System. Ecol. 32:391-7, 2004

With E.A. Silva & J.A. Takahashi. An interesting backbone rearrangement and novel derivatives from the biotransformation of trachyloban-19-oic acid by Rhyzopus stolonifer. J. Braz. Chem. Soc. 13(1):101-5, 2002

With L.P.S. Pimenta, F.C. Nascimento, A.C.S. Assunção & M.A.D. Oliveira. Laurifolin, a novel acetogenin from Rollinia laurifolia leaves. Tetrahedron Lett. 42:8433-4, 2001

With J.P. Leite, L. Rastrelli, G. Romussi, J.H.Y. Villegas, C. Pizza & W.W. Villegas. New flavonoid glycosides from the infusion of Maytenus aquifolium and M. ilicifolia leaves. Rev. Latinoam. Quim. 28:179-80, 2001 (Suppl.)

With F.C. Braga, M.G.R. Duarte & J.D. Souza Filho. Isolation and structure elucidation of a new flavonol glycoside from the lyophylized infusion of Maytenus ilicifolia leaves (2001)

With L.P. Santos, M.A.D. Boaventura, N. Sun & J.M. Cassady. Araticulin, a new bis-tetrahydrofuran polyketide from Annona crassiflora seeds. Phytochem. 42:705-7, 1996

With D.P. Lima & D.S. Raslan. New nitrogen derivatives of podophyllotoxin and a novel access to dehydroanhydropicapodophyllin. Synth. Comm. 24(18):2675-83, 1994

With L.P. Santos & M.A.D. Boaventura. Crassiflorina, uma acetogenina tetraidrofurânica citotóxica de Annona crassiflora. Quim. Nova 17(5):387-91, 1994

With D.S. Raslan, E. Chiari & D.S. Duarte. Lychnophoic acid, a new trypanocidal agent and other constituents of Lychnophora pinaster Mart. (1994)

With D. Cortes, H. Dadoun & R.L.R. Paiva. Nouveaux alcaloides bis-benzylisoquinoleiques isolés des feuilles de Aristolochia gigantea. J. Natur. Products 50(5):910-4, 1987

With F. Carazza & J.G.S. Maia. Geovanine, a new azanthracene alkaloid from Annona ambotay Aubl. Phytochem. 26(9):2650-1, 1987

With M.O.F. Goulart, A.E.G. Santana, G.G. Oliveira & J.G.S. Maia. Novos alcalóides de Guatteria dielsiana R.E. Fries. Oreades 8(14-5):341-5, 1982

With T.M. Braz, F.R. Bauer, L. Siqueira & N.C.S. Silva. Laevigatin, a sesquiterpenoid furan from Eupatorium laevigatum Lam. Tetrahedron Lett. 2653:4, 1978

Developed benzyleugenol, a convulsant drug (1978)

With E. Wenkert, H.E. Gottlieb & Hagmann isolated emmotines, terpenoids from Emmotum nitens (1974)

With R. Braz Filho, V.T. Shaat, M.F.F. Leite & O.R. Gottlieb. Novel constituents of Virola multinervia. Cien. Cult. 25:563, 1973


DEVELOPED METHODS/TECHNIQUES

With S.K.V. Bertolucci, A.B.D. pereira, J.E.B.P. Pinto, J.A.A. Ribeiro & F.C. Braga. Development and validation of an RP-HPLC method for quantification of cinnamic acid derivatives and kaurane-type diterpenes in Mikania laevigata and Mikania glomerata. Planta Medica 75:280-5, 2008

With M.A.F. Brandão & V. Snieckus. Combined directed metalation cross coupling strategies. A regiospecific route to heteroring annelated ortho-naphthoquinones and a short synthesis of β-lapachone. Tetrahedron Lett. 34:2437, 1993

A short and efficient route to azafluorenones (1988)

Ortho-furanonaphthoquinones. A simple route to angular analogs (1988)

Process for production of threonine methyl esther (1987)


PATENTS

With M.F. Dolabela, M.T. Martins, D.L.N. Brandão, E.S. Borges, S. Percario, A.M.R. Marinho et al. Method for producing a plant extract and fraction, pharmaceutical compositions and use thereof WO20150132421 (2013)

With A.O. da Silva, A.D. Almeida, D.L.N. Brandão, E.S. Borges, E.F. Mota, F. Vasconcelos et al. Composition and use of Aspidosperma nitidum ethanolic extract as antiplasmodic agent BR 10 2012 019426 A2 (2012)

With M.F. Dolabela, F.D. Rocha, R.L.R.P. Jacome, R.M.T. Neiva, F.M.A. Gomes & R.C. Paula. Pharmaceutical compositions containing extract and/or bark fractions of Aspidosperma subincanum and use BR 13 2012 033307 3 E2 (2012)

With M.F. Dolabela, G.C. Brandão, M.T. Martins, E.S. Borges, D.L.N. Brandão et al. Composition of ethanolic extract and dichloromethane fraction rich in naphthoquinones and use as antimalarial agent BR 10 2012 0194236 A2 (2012)

With E.G. Kroon & G.C. Brandão. Pharmaceutical composition containing Myracrodruon urundeuva and use BR 10 2012 001453 0 A8 (2012)

With E.G. Kroon & G.C. Brandão. Antiviral pharmaceutical compositions containing extract, fractions and/or isolated compounds of Arrabidaea pulchra and use PI1106466-8 A2 (2011)

With F.P. Varotti & R. Batista. Anti-malaria pharmaceutical compositions containing kaurenic diterpene derivatives BR PI1015495-7 (2010) & WO2012 083408 A8 (2012) 

With E.G. Kroon & G.C. Brandão. Pharmaceutical composition containing acylated mangiferin derivatives and use PI1001164-1 A2 (2010)

With M.F. Dolabela, F.D. Rocha, R.L.R.P. Jacome, R.M.T. Neiva & F.M.A. Gomes. Tandardized extract and fraction of barks of Aspidosperma parvifolium and/or ulein and their pharmaceutical composition PI0905584-3 A2 (2009)

With M.F. Dolabela, M.T. Martins, D.L.N. Brandão, E.S. Borges, S. Percario, C.C. Quaresma et al. Process for obtaining ethyl acetate and methanolic fractions and antimalarial use BR 10 2012 0118645 A2 (2006)