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Hsiang-fu Kung

Hsiang-fu Kung, Chinese molecular geneticist (04 September 1942 – 17 June 2019)




Developed the first human interferon of world market (Hoffmann La Roche Inc.)
 

First to purify and crystallize recombinant human leukocyte interferon α A


First to prove the transforming activity of Ras protein and establish the roleof phospholipase C and nerve growth factor in Ras-mediated signal transduction pathways
 

Developed anti-cancer drug targeting on the activity of Ras farnesyl-protein transferase
 

Demonstrated the physiological roles of bone morphogenetic protein-4 (BMP-4) during embryonic development in Xenopus embryo
 

Elucidated the BMP4 signaling pathways and demonstrated the role of GATA-1 b protein in the inhibition of neurogenesis
 

Purified several anti-tumor and anti-viral agents from TCM and elucidated their mechanisms of action that were patented
 

Identified the active anti-HIV components in HCG preparations
 

Held many patents in United States of America