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Hyam Isaacs

Hyam Isaacs, South African neurologist (1927 –

Described Isaacs-Mertens syndrome  or neuromiotonia

A syndrome of continuous muscle-fiber activity. J. Neurol. Neurosurg. 24:319-25, 1961


With M.E. Badenhorst. False-negative results with muscle caffeine halothane contracture testing for malignant hyperthermia. Anesthes. 79:5-9, 1993

With M.E. Badenhorst. Dominantly inherited malignant hyperthermia (MH) in the King-Denborough syndrome. Muscle Nene 15:740-2, 1992

With M.E. Badenhorst & C. du Sautoy. Myophosphorylase B deficiency and malignant hyperthermia. Muscle Nerve 12:203-5, 1989

Stiffman syndrome in a black girl. J. Neurol. Neurosurg. Psychiatry 42:988-94, 1979

With J.J.A. Heffron. Malignant hyperthermia syndrome: evidence for denervation change in human skeletal muscle. Klin. Woch. 54:865, 1976

With J.J. A. Heffron. Morphological and biochemical defects in the muscles of human carriers of the malignant syndrome. Br.J. Anaesthes. 47:475, 1975

With J.J.A. Heffron & M. Badenhorst. Central core disease: a correlated genetic histochemical, ultramicroscopic and biochemical study. J. Neurol. Neurosurg. Psychiatry 38(12):1177, 1975

With G. Muncke. Idiopathic cardiomyopathy and skeletal abnormality. Am. Heart J. 90:767-73, 1975

With M.B. Barlow. Central core disease associated with elevated creatine phosphokinase levels: two members of a family known to be susceptible to malignant hyperpyrexia. S. Afr. Med. J. 48:640-2, 1974

With J.J.A. Heffron. The syndrome of “continuous-muscle-fibre activity” cured: further studies. J. Neurol. Neurosurg. Psychiatry 37(11):123-5, 1974

With M.B. Barlow. Malignant hyperpyrexia. J. Neurol. Neurosurg. Psychiatry 36(2):228-47, 1973

With M.B. Barlow. Malignant hyperpyrexia during anaesthesia: possible association with subclinical myopathy. Br. Med. J. 1:275, 1970

Quantal squander. S. Afr. J. Lab. Clin. Med. 10:93-5, 1964

The treatment of myotonia congenita. S. Afr. Med. J. 33:984-6, 1959 

Familial pes cavus, absent tendon jerks and extensive muscular atrophy. S. Afr. Med. J. 32:830-2, 1958