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Geoffrey Falkson

Geoffrey Falkson, South African oncologist and chemotherapist (Pretoria 09 August 1932 – 10 January 2019)

Authored over 400 papers

Demonstrated the potentiation of ionizing radiation and fluorinated pyrimidines in the treatment of gastrointestinal cancer

Fluorinated pyrimidine as potentiators of ionizing radiations in the treatment of stomach cancer in man. Thesis (1964)


With A.M. Chedid, L.M. Ryan, Y. Dayal & B.C. Wolf. Morphology and other prognostic factors of hepatocellular carcinoma. Arch. Pathol. Labor. Medic. 123(6):524-8, 1999

With J.I. Raats & H. Falkson. Fadrozole hydrochloride, a new nontoxic aromatase inhibitor for the treatment of patients with metastatic breast cancer. J. Ster. Biochem. Mol. Biol. 43:161-5, 1992

With C. Falkson & H. Falkson. Improved results with the addition of interferon alpha 2a to dacarbazine in the treatment of patients with metastatic malignant melanoma. J. Clin. Oncol. 9:1043-8, 1991

With H.C. Falkson & C.I. Falkson. High versus low dose granisetron, a selective 5HT3 antagonist, for the prevention of chemotherapy-induced nausea and vomiting. Investig. Drugs 8:407-9, 1990 

With H.C. Falkson & C.I. Falkson. The effect of chemotherapy with or without GnRHA on serum hormone levels in premenopausal women with breast cancer. Proc. Am. Soc. Clin. Oncol. 9:25, 1990

With H.C. Falkson, A. Cnaan, A.J. Schutt & L.M. Ryan. Prognostic factors for survival in nhepatocellular carcinoma. Cancer Res. 48:7314-8, 1988 

High-dose medroxyprogesterone acetate plus mitomycin-C or vindesine in the treatment of advanced breast cancer. Am. J. Clin. Oncology - Cancer Clin Trials 2:431-4, 1988 

With R.S. Gelman & F.J. Pretorius. Age as a prognostic factor in recurrent breast cancer. J. Clin. Oncol. 4(5):663-71, 1986

With B. Klein & H. Falkson. Hematological toxicity: experience with anthracyclines and anthracenes. Exp. Hematol. 13:64-71, 1985 (Suppl. 16)

With J.M. McIntyre, A.J. Schutt, B.J. Coetzer et al. Neocarzinostatin versus m-AMSA or adriamycin in hepatocellular carcinoma. J. Clin. Oncol. 2:581-4, 1984

With D.A. Vorobiof, J.H. Lerner et al. A phase II study of M-AMSAin patients with malignant mesothelioma. Cancer Chemotherap. Pharmacol. 11:94-7, 1983

With H.C. Falkson & I.W. Simson. Non-Hodgkin’s lymphoma in pregnancy. Cancer 45:1679-82, 1980

Chemotherapy studies in primary liver cancer: a prospective randomized clinical trial. Cancer 42(5):2149-56, 1978

With H.C. Falkson. Further experience with isophosphimide (1976)

With H.C. Falkson. Fluorouracil, methyl-CCNU and vincristine in cancer of the colon. Cancer 38:1468-70, 1976

Therapeutic approaches to hepatoma. Cancer Treat. Rev. 2:73-6, 1975

With E.G. Van Edin & H.C. Falkson. Fluorouracil midazole carboxamide dimethyltriazeno, vincristine and bischloroethylintrourea in colon cancer. Cancer 33:1207, 1974

With J.J. Van Dyck, H.C. Falkson & A.M. Van der Merwe. Unexpected toxicity in patients treated with iphosphamide. Cancer Res. 32:921-4, 1972

An annotation on the treatment of disseminated breast cancer in premenopausal women. S. Afr. J. Surg. 10:41-4, 1972

With E.W. Geddes. Malignant hepatoma in the Bantu. Cancer 25(6):1271-8, 1970

Behandeling van Gevorderde Longkanker. Geneeskunde 11:147, 1969

With H.C. Falkson. Erythroleukemia. S. Afr. Med. J. 42:1291, 1968

With H.C. Falkson. The clinical testing of anti-cancer drugs and the criteria for response to these drugs. S. Afr. Cancer Bull. 10:5, 1966

With E.J. Schulz. Skin changes caused by cancer chemotherapy. Br.J. Dermatol. 76:309-14, 1964

With H.J. Snyman. Experience with chemotherapy of cancer at the University of Pretoria. Acta Union Int. Contre Le Cancer 20:439-66, 1964

With E.J. Schulz. Endoxan alopecia. Br.J. Dermatol. 72:296-301, 1960

Chemotherapie van Primere Lewerkarsinoom. Spekulum 3:5-11, 1959  


Special Award for Meritorius Service, Eastern Cooperative Oncology Group, United States (1997)

International Award of Imminent Scientist of the Decade 1990-99