Eduardo Hernán Charreau, Argentine molecular endocrinologist (San Fernando, Buenos Aires Province 27 May 1940 – Buenos Aires 23 March 2019) Authored over 200 works Discovered novel metabolic pathways in normal and pathologic tissues First to describe some molecular insulin and prolactin induced mechanisms about steroid metabolism of Leydig and luteal cells and in accessory sexual glands
Characterized the receptor for luteinizing hormone and prolactin in Leydig cells Discovered that ovary resistance syndrome is due to circulating antibodies that affect the follicle stimulating hormone Developed and characterized a prostagen induced mammary carcinogenesis model
First to report interaction between progestin and the signal transduction pathways HRG/ErbB in mammary cancer (1999)
Explained
the molecular failures of the reproductive system in experimental diabetes Performed
molecular characterization of the growth promoting effects of progestin
hormones on mammary carcinogenesis Showed the activity of juvenile hormone analogues on steroid biosynthesis |
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