Alphabetical List‎ > ‎C‎ > ‎

Carlos Eugenio Cardini

Carlos Eugenio Cardini Bellati, Argentine biochemist (Buenos Aires 09 December 1911 - 1991)

From Italian grandparents


With R. Caputto, L.F. Leloir and A. Paladini discovered sugar nucleotides, determined its chemical nature and showed that play a key role in sugar interconversion and polysaccharides synthesis (1948)
 
With L.F. Leloir established that in plant tissues two reactions can lead to synthesis of sucrose (1953-5)

With L.F. Leloir suggested the involvement of uridine diphosphate N-acetylglucosamine in chitin synthesis (1953)

With L.F. Leloir and J. Chiriboga synthesized sucrose (1955)

With L.F. Leloir described an alternative mechanism for synthesis of glycogen from UDP-glucose and glycogen synthase (1957)


With Yamaha & Leloir demonstrated that glycosides synthesis via UDPG (1960)

With Fekete & Leloir discovered enzymatic system that catalyzes sucrose transformation into starch (1960)

With Rosalía B. de Frydman & Luis F. Leloir demonstrated that phytoglycogen biosynthesis from ADP-glucose (1965)


METHODS/TECHNIQUES

With Cabib and Leloir suggested the use of sodium chloride in dilute hydrochloric acid for eluting nucleotides from a column of ion-exchange resin and introduced the technique of purifying nucleotides with Norite 

Developed a new procedure for determination of choline

With A.D. Marenzi. The colorimetric determination of choline. J. Biol. Chem. 147:363, 1943

A procedure for preparation of β-α-nitrosonaphthol and an assay for cobalt

With W. Jung & M. Fuksman. El  β-α-nitrosonaftol como reactive del cobalto. II. Colorimetria y fotometria del cobalto. Anal. Asoc. Quim. Arg. 21:191, 1943 

With A.D. Marenzi developed a colorimetric micromethod for the determination of total and unsaturated fatty acids in blood


PAPERS IN NATURE REVIEW  

With T. Yamaha. Biosynthesis of plant glycosides from uridine diphosphate glucose. Nature 182 (4647):1446-7, 1958

With M.A. Rongine de Fekete & L.F. Leloir. Mechanism of starch biosynthesis. Nature 187:918-9, 1960

With J.C. Trivelloni & E. Recondo. Adenosine diphosphate glucose and glucoside biosynthesis. Nature 195:1202, 1962   


EPONYMY

Leloir pathway or Leloir cycle or Leloir-Cardini cycle (galactose metabolism)

Leloir-Cardini enzyme (UDP glucose glycogen transglucoxylase)