Carlos Chagas Filho, Brazilian biophysicist (Rio de Janeiro 12 September 1910 – Rio de Janeiro 16 February 2000) Son of
Carlos Chagas (filho means son in Portuguese)
ACHIEVEMENTS
Authored
about 200 scientific papers Described
action of curare and curare-like action substances in electro plaque Discovered
that electro plaques have 2 kinds of excitability Explained
operating mechanism of Electrophorus electricus
electrical organ Discovered
central nucleus that commands electrical discharges in medula oblongata of the
eel Described
micro heterogeneity of desmin in electrical organ of poraquê (Electrophorus electricus) Identified
nicotinic receptor in poraquê (Electrophorus
electricus) Showed that
acetylcholine played a role in the process of electric discharges of Electrophorus electricus Isolated
the acetylcholine membrane receptor of electrical fishes Introduced
notion of specific and unspecific receptors With D. Bovet & L. Sollero described the in vivo curarisation of the electric organ of the Electrophorus electricus (1953) With C. Chagas, M. Françon & H.C. Parreira. Nouvelle methode d’etude des gradientes d’indice applicable a la electrophorese. An. Acad. Bras. Cien. 27:385, 1955 On the use of a multivibrator as a Geiger-Muller counter external quenching circuit With M.X. de Oliveira. Electrogênese em cultura de tecidos (1946) With A. Leão, M.F. Moreira & M.S. Santos. On the low voltage discharge of the electrophorus. Nature (1946) With D. Albe-Fessard & H.M. Ferreira. Sur l’existence d’un systeme directment excitable dans l’organe eléctrique. C.R. Acad. Sciences 232:1015-7, 1951 With D. Albe-Fessard & H.M. Ferreira. Sur l’existence d’un systeme effecteur de la décharge electrique des Electrophorus electricus. Anais Acad. Bras. Ciencias (1951) Técnica de registro dos potenciais elétricos de miocárdio em cultura
HONORS President,
Pontifical Academy of Sciences (1973-90) Doctor Honoris Causa, Université de Paris
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