Wilson Teixeira Beraldo, Brazilian pharmacologist (Silvianopolis, Minas Gerais State 20 April 1917 – Belo Horizonte 28 July 1998)
ACHIEVEMENTS
Known internationally as an expert in vasoactive polypeptides (about 2,000 citations)
Co-discovered bradykynin With M. Rocha e Silva & G. Rosenfeld. Bradykynin, a hypotensive and smooth muscle stimulating factor released from plasma globulin by snake venoms and by trypsin. Am. J. Physiology 156:261-73, 1949. Demonstrated bradykinin release in anaphylactic and peptonic shocks Formation
of bradykinin in anaphylactic and peptone shock. Am. J. Physiol.
163(2):283-9, 1950
Demonstrated urinary kallikrein is of renal origin Substance U: a depressor and smooth-muscle stimulating present in urine. Am. J. Physiol. 171(2):371-7, 1952 Demonstrated that granulations of mast cells store histamine With L.C.U. Junqueira, I. Mota e Albuquerque & R.G. Ferri. Intracellular distribution of histamine. Nature 174:698-9, 1954 Rat blood pressure as a diagnostic procedure for pheochromocytoma. Arch. Int. Pharmacodyn. Ther. 126:37-42, 1960 Papers in top journals (see above) With M.R.E. Silva. Effect of cations upon recovery of the guinea pig gut from inhibition of antihistaminics. Science 108(2798):162-3, 1948 With L.C.U. Junqueira, I. Mota & A.G. Ferri. Action of peptone on mastcells of the dog. Nature 173:547, 1954 With O.B.
Henriques & M. Fichman. Bradykinin-releasing fator from Bothrops jararaca venom. Nature
187:414-5, 1960 With G. Gazzinelli, M.M. Guia, A.G. Neves, J. Pudles & W. da Silva. Purification of the toxic fractions from Ascaris lumbricoides and their effect on the guinea pig. Nature 190:813-4, 1961 MEMBERSHIP Member, New York Academy of Sciences |
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