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Pushpa Mitra Bhargava

Pushpa Mitra Bhargava, Indian biochemist (Ajmer District, Rajasthan State 22 February 1928 - Hyderabad 01 August 2017)


Authored over 125 research papers


ACHIEVEMENTS

First report on the identification of genus Pseudomonas from Continental Antarctica

With S. Shivaji, N. Shyamala Rao, L. Saisree, V. Sheth & G.S.N. Reddy. Isolation and identification of Pseudomonas spp. from Schirmacher Oasis, Antarctica. Appl. Environ. Microb. 55:767-70, 1989


With V.N. Rao. Isolation, characterisation and possible mode of action of antiseminalplasmin, a new protein that inhibits the antimicrobial activity of seminalplasmin. Biochem. J. 227:609-19, 1985


Four new and unusual proteins from bovine seminal plasma. Biochem. Soc. Trans. 9:540-3, 1981


Discovered semilplasmin or caltrin

With E.S.P. Reddy. Seminalplasmin: an antimicrobial protein from bovine seminal plasma which acts in E. coli by specific inhibition of rRNA synthesis. Nature 279:725-8, 1979


Regulation of cell division and malignant transformation. A new mode of control by uptake of nutrients. J. Theor. Biol. 68:103-37, 1977


With T. Pallaiah & E. Premkumar. Aminoacyl-transfer RNA synthetase recognition code-words in yeast transfer RNAs: a proposal. J. Theor. Biol. 29:447-69, 1970


Co-discovered the anticancer drug 5-fluorouracil

With C. Heidelberger, K.C. Leibman & E. Harbers. The comparative utilization of uracil-2-C14 by liver intestinal mucosa and Flexner-Jobling carcinoma in the rat. Cancer Research 17(5):399-404, 1957

  

METHODS

With S. Shankarnarayan, C.B.S. Dutt, S. Shivaji & R. Manchanda. A cryosampler payload for aseptic air sample collections at stratospheric altitudes using balloons (2006)


Developed a simple computer program to locate repeating subsequences of all possible lengths in a given nucleic acid

With M.W. Panditr, A. S. Kolaskar & T.A. Thanaraj. Analysis of repeating oligonucleotide sequences in ribonucleic acids using an Apple II microcomputer (1986) 


With S.T. Jacob. A new method for the preparation of liver cells in suspension. Exper. Cell Research 27:453-67, 1962


With S.H. Zaheer. A new synthesis of some derivatives of 4,4'-stilbenediol. Nature 171:746-7, 1953


OTHER CONTRIBUTIONS

Discovered 9 new bacterial species from Antarctic Continent and stratosphere

With K.H. Scheit & E.S.P. Reddy. Seminal plasmin is a potent inhibitor of E. coli RNA polymerase in vitro. Nature 279:728-31, 1979 

Incorporation of radioactive aminoacids into the proteins of bull spermatozoa. Nature 179:1120-1, 1957


HONORS

Bhargavaea Shivaji, Manorama, Pindi & Reddy 2009 (Bacteria)


LINKS

www.pmbhargava.com